In recent years, with the rapid development of mobile communication network, the network service quality problem has been paid more and more attention, users of mobile network performance requirements are increasingly high. The network quality to improve network covering need improvement, the competition between different network operator has intensified. Thus the network quality stand or fall already more and more be what people value, which requires deeper network optimization. Network optimization refers to formally put into operation network parameter acquisition, data analysis, and find out the influence the quality of the network operation reasons and through parameter adjustment and take some technical means, making the network to achieve the best operation state, making the existing network resources to get the best benefit, but also for network future maintenance and construction plan put forward reasonable Suggestions. While in network optimization, the influence factors on the quality of the network operation, there are many aspects, such as frequency planning, hardware malfunction, wireless environment, traffic distribution, terminal parameter setting and adjacent area relationship Settings etc, including mobile communication system the interference issues that affect the wireless network optimization.some, connection system such as indicators of important factor. It not only affected our network of normal operation, but also influences the user call quality, the user is one of the main reasons ShenGao. This text discusses internal interference analysis of the causes and research, combining produce internal interference problems of real case, accurate to network interfering problems appeared in the localization, set the scheme, solve the problems interference network problems, improve the network operation quality.